Biocombination No. 20


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Skin Diseases • Supportive drug in the treatment of skin diseases.



Indications: Scurfy eruption on the scalps and in the face of children; eczemas and similar complaints due to uterine disorders, acne, pemphigus, herpes, erysipelas, crusta lactea and similar eruptive diseases.

Diseases affecting skin is very frequent and of various types, causes, severity and complexities. Skin is made up of epidermis and dermis. The later consists of fibrous tissues, blood vessels, nerves, sebaceous & sweat glands and hair follicles. Differentiation is must to have maximum result from the Bioplasgen/Biocombination 20.

1. Abnormality of sensations like itching (pruritis) anaesthesia, and hyperaesthesia are generally of nervous origin. Itching could also be due to local factors or allergens. A diffuse area of redness with dilated capillaries which disappear on pressure is called erythema. It is common in drug rashes. Round spots of measles, rubella and syphilis which are red or copper-coloured and not raised above the surface of the skin are called macules, whereas, the small solid elevated pimple-like eruption is called papules. Vesicles are small-elevated blisters containing clear fluid and if they are large, half an inch or more in diameter, it is called bullae. Vesicles containing pus (purulent fluid) which on rapture produces crusts or scabs are known as pustules. Scales are dried parts of the epidermis and crusts caused by drying purulent exudates which are also called scabs. Wheal is the round or elongated elevation of temporary nature as in urticaria which may be small or large, local or generalised. Abrasions technically are called excoriations and loss of tissues is an ulcer. Haemorrhagic patches are petechiae and large bruises are called ecchymoses.

2. The causes of skin problems may be exogenous like trauma, accidents, burns, acid or alkali action, chemicals, radiation, detergents, soap and many allergens or endogenous due to infections, toxins, drugs, allergens, disorder of circulation, tumours and even psychosomatic causes in sensitive persons.

3. Acne, boils and carbuncles can be grouped together. Accumulation of fat/grease in ducts of sebaceous glands is acne, sometimes of infectious origin whereas boil or furuncle is deep-seated inflammation, painful with pus terminating with bursting. A carbuncle is a larger, deeper lesion involving subcutaneous tissues. Impetigo is contagious, the small red spots rapidly develop into vesicles and pustules and rapture. It is found more in children. Sycosis is another rush condition of the beard area of adults and is due to infection.

4. Dermatitis or eczema is non-contagious inflammation breaking out the skin which may be dry or wet normally caused by external irritants; if sebaceous glands are involved, it is known by the more specific term seborrhoea.

5. Some parasites also invade like tinea (ringworm), pediculosis (lice) or scabies (an insect sarcoptes scabies) causing lesions and itch.

6. Herpes is a painful inflammatory condition with a cluster of vesicles associated with fever more localised on nerve areas. It is viral in origin. In urticarea wheels appear and they are pure of allergic origin. Allergic cutaneous oval Swelling due to circulating toxin is called erythema nodosum.

7. Psoriasis is characterised by presence of red patches covered by silver-grey scales on various parts of body without affecting the general health. It is common in the tropics and sometimes associated with rheumatoid arthritis.

8. Disorders of pigmentation are due to diseases like jaundice, anaemia, varicose veins, ulcers, burns or due to disease like leucoderma.

Note: For the optimum effect of Bioplasgen/Biocombination 20, please use in the indicated area for use. In other cases, it is used with specific medicines as supplement for quick relief.

Composition: Calcarea fluorica 6x, Calcarea Sulphuricum 6x, Kalium sulphuricum 3x, Natrum muriaticum 6x, Natrum sulphuricum 3x in equal proportion.

Proven indications of the ingredients within the claimed sphere of action:

Calcarea fluorica: Itis indicated for hard elevated edges of ulcers, scar tissues, chaps, fissures, crack, suppuration with callous hard edge, swellings, indurated enlargements and whitlow or marked whiteness of skin.

Calcarea sulphurica: Itis indicated for wounds, bruises, unhealthy skin discharging pus, yellow, purulent forming crusts, scabs, pimples and dry eczema.

Kalium sulphuricum: It is indicated for psoriasis, eczema, burning, itching, papular eruption, nettle rash, polyp, epithelioma, seborrhoea, and ringworms. It lowers mucous & serous discharges, as well as inflammations.

Natrum muriaticum: Itis suited to greasy/oily skin, dry eruptions, fever blisters, urticaria, itching and burning, crusty eruptions in bends of limbs, scalp or behind ears, eczema – raw, red and inflamed, diseases of hair follicles, alopecia & hives.

Natrum sulphuricum: It covers watery blisters, sycotic excrescences, wart-like red lumps all over the body, jaundiced skin and symptoms of itching while undressing.

Contra-indication: Nil. It is a safe, non-toxic drug and can be used along with other medicines.

Dosage: Adults 4 tablets, children 2 tablets, at a time, four times a day at intervals of three hours. Presentation: Tablets of 100 mg in bottles of 20g.


Alcohol: There is no reported safety concern if it is taken with alcohol.

Pregnancy: It is safe to take during pregnancy.

Driving: It is safe to use during driving.

Breastfeeding/Lactation: It can be used while breastfeeding.

Kidney: There is no known contraindication with kidney diseases.

Sugar: It does not affect blood sugar levels.

Immunity: It will not affect the immunity of an individual.

Liver: It is safe for the liver.

High blood pressure/Hypertension: It is safe to use in patients with hypertension.

Low blood pressure: It will not lower the blood pressure.

Heart: It does not contain any ingredient which will affect the heart.

Mentally retarded: There is no known contraindication with mentally retarded persons.

Post covid impacts: There is no known contraindication with post covid impacts.

Diarrhea: It will not cause any diarrhea.

Gastric: There are no known effects on the gastrointestinal system.

Empty stomach: It is preferably to be taken after a meal.

Skin allergy: There is no skin allergy when using Biocombination No.20. It is a well-indicated medicine for skin complaints.

Habit: It is not a habit-forming product.

Overdose: In case of overdose, drink lots of water or consult a physician.

Storage: It has to be stored in a cool dark place, away from sunlight and strong-smelling substances.

Temperature: The temperature should be 25 degrees centigrade.

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